Wednesday, April 29, 2020

Microplates Launch a new product Microlute SLE – Supported Liquid Extraction

Microplates have just launched a new product called Microlute SLE – Supported Liquid Extraction for Porvair Sciences. With this new product created by Microplates, you can extract a variety of acidic, basic, and neutral analytes from various biological or aqueous samples, done very quickly using a robust method of liquid extraction.
This method of extraction is done so quickly with the help of Microlute SLE. The Microlute SLE 96 well plates and cartridges use selectively sourced diatomaceous earth (DE) as the solid support. This means it can increase the absorption of the aqueous solutions, which results in a more straightforward recovery of analytes from samples, and also a greater reproducibility.
There is a wide range of features associated with the Microlute SLE product. It has a quick and simple recovery due to the minimal number of steps needed, so you’ll have a quick clean up, while also securing over 99% recovery of contaminant-free analytes, so little injuries are involved.
The MicroluteTM SLE can process up to 96 samples, so if you are interested in a product like this for your laboratory, this is perfect for laboratory automated workflows. One ideal feature of the Microlute SLE is its efficient removal of proteins with a low risk of contamination, so you’ll have clean samples and also less cleaning-up time, a great bonus if you purchase this product.
Microplates consider this product to be much better than LLE as there are minimal requirements involved with the Microlute SLE such as no inversions, no shaking and no pipetting. With standard liquid extraction, there tend to be sample handling issues; however, not with Microlute SLE.
The method of its sample preparation enables the user to have an effective and efficient workflow from its reliability to its ease of clean-up samples for chromatography analysis. So, how does the Microlute SLE work exactly? Well, Microplates suggest you add your sample on to the plate or cartridge, wait until complete absorption of the aqueous solution has taken place and you can then ‘elute’ analytes in your preferred solvent.
The MicroluteTM SLE is available in 96 well plate and cartridge formats with a 200µl (and 400µl) maximum load volume(s). This sample preparation product is suitable for plasma, serum, oral fluids, urine or other aqueous-based solutions. For more information about this new range from Microplates, or if you have any queries about an immiscible solvent or emulsion formation, get in touch with Microplates today, they will be happy to assist you.
The MicroluteTM SLE – Supported Liquid Extraction is another new product offered by Microplates, alongside the Microlute PPpp plate, both of which can be found online at https://www.microplates.com/microlute-sle/. You can find these products under sample preparation, and there is a detailed description of the products also. If you’re interested, you can add the amount you want of a particular product for enquiry. The SLE is very easy to use, and it is an excellent method of liquid extraction, so, if you’re looking for a product like this, consider the MicroluteTM SLE, it has several features, and it can be used with vacuum and positive pressure systems too.
About Microplates
Porvair Sciences, specialists in the manufacture of microplate products, serve Life Sciences, Biotechnology, R&D and Molecular Biology with microplate solutions for all applications, from sample preparation to high throughput screening via our global distributor network.
Contact Microplates
Clywedog Road South
Wrexham
LL13 9XS
United Kingdom
+44 (0)1978 661144
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Microplates Launch a New Product, the Microlute™ Protein Precipitation Plates

Microplates have just launched a new product, the Microlute™ Protein Precipitation Plates. During biological sample preparation in the lab, the biological samples commonly contain proteins that interfere with downstream applications so Microplates created the Microlute™ Protein Precipitation Plates. This product uses the CRASH method, meaning the protein is denatured with acetonitrile and the flocculant filtered out, therefore allowing 96 samples to be handled at one given time.
Microplates explain that the protein ‘crashes’ out of solution. Hence, the reason the new product is called protein precipitation, is that the protein precipitates directly in each well when acetonitrile is added.
As mentioned, this is a new product offered by Microplates, and with this product comes many benefits. One main advantage is that it can solve all common problems associated with the CRASH technique of protein clean-up.
One common problem is that there can be leakage involved with samples. But with the protein precipitation filter plate, its novel dual filter (also known as the frit) and hydrophobically treated matrix, there will be no leakage of the sample through the plate before the application of vacuum.
As well as this new product they are offering, Microplates have optional drain cap and top cap mats available for those wishing to use vortex sample mixing.
Microplates have three available protein precipitation plates on their site, and the first PP plate is the P3 Protein Precipitation Plate High Efficiency (untreated frits) packed individually rigid shell. The well shape is square, and the volume is 2ml, and it is made of polypropylene.
Then you have the P3 Protein Precipitation Plate packed individually in a rigid shell and the P3 Protein Precipitation Plate – bulk packed in a bag of five, no individual shells. Each one of these PP filter plates is made up of Vyon HDPE for its filter material, and it has a long filter drip director. However, the first comes in rigid shells, whereas the bulk packed one consists of a bag of five with no individual shells.
Microplates have even provided a video about biological sample preparation with the Protein Precipitation Plate P3 in the Porvair Sciences research facility. This video is handy as it gives an overview of the new product by preparing a sample of serum for analysis by LCMS, and this requires a professional to remove some of the protein that would usually block up the columns in the liquid chromatograph, and they do this with the new PP plate.
From the video, you will see how quick and efficient Microplates new product is at helping you prepare your biological samples for analysis by LCMS.
You must get in touch with Microplates today and enquire about their new product – Protein Precipitation Plates. The Microlute™ Protein Precipitation Plates was created to provide you with the most benefits and to avoid any leakage of your samples in the lab.
Check out the pp filer plate online at https://www.microplates.com/protein-precipitation-plates/ where you can read more about each PP filter plate, download protocol, application note and also watch the uploaded video about the new product. If you have any questions or queries about the latest product, you can send an email to patricia.deeside@gmail.com or call +44 (0)1978 661144.
About Microplates
Porvair Sciences, specialists in the manufacture of microplate products, serve Life Sciences, Biotechnology, R&D and Molecular Biology with microplate solutions for all applications, from sample preparation to high throughput screening via our global distributor network.
Contact Microplates
Clywedog Road South
Wrexham
LL13 9XS
United Kingdom
+44 (0)1978 661144
Posted by at No comments:
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