Microplates: 2019

Wednesday, December 4, 2019

Microplates Provides a Full Range of 96-well Microplates Including the 48 and the 384

Microplates provide you with a full range of 96-well microplates including the 48, and the 384, and you have a choice of glass fibre, nylon, PVDF or polyethylene filtration materials and well volumes ranging from 350 l to 5 ml. The filtration plates are used in their purest form to remove particulate matter from liquid. Either the particulate matter or the filtrate is needed for further study. Microplates have a range of filter plates to suit most filtration applications.

At Microplates, they have optimised filter plates for applications including cell harvesting, DNA separations, binding studies, Plasmid isolation, general filtration and sample clean-up.

First, you have the solid transparent assay plate 96-well clear plates which offer the perfect mix of affordability and high quality. Not only are they manufactured from high-quality crystal polystyrene, but they also have a flat bottom for spectrophotometric work and a v-bottom which helps to minimise residual liquid. It is robot compatible with working volumes from 275l down to 10l and a round bottom for cell/particulate collection.

The 96 well microplate is available in 300 l, 400 l, 800 l and 2ml. For example, the 96-well microplate 2ml suits most filtration applications, including this range of 96-well, 2ml, microplates which contains a choice of glass fibre, nylon, PVDF or polyethylene filtration materials.

Porvair Science’s range of solid bottom 96-well assay plates is designed explicitly for absorbance, fluorescence, luminescence and scintillation applications. The design uses the most popular 96-well format with standard ‘chimney’ wells to overcome optical crosstalk and contamination.
These plates are designed to give optimum results from any instrument which reads from the top of the plate.

Some highlights of these plates include the composite black/white plate which is ten times more sensitive than a standard white plate for chemiluminescence assays. As well as the following listed below, which include:

Black plates designed for top reading fluorescence instruments
Black plates have low background fluorescence and minimise light scattering
White plates maximise signal for luminescence readers
A highly polished well to give better readings

For the 384-well plate, you have a range of plates to choose from such as the 384-well 140 l polypropylene, long drip glass fibre, mean pore size 1.2 m and mean pore size 0.7 m. As well as a long drip and no filter, a long drip UHMW pore size 25 m and 5.0 m.

The 384-well assay plates from Porvair Sciences are available in black, white and bright. A significant advantage of these is that they have been optimised for fluorescence, luminescence/scintillation and ELISA/turbidity measurements. There are two working volumes: 30l/well or 120l/well. All 384-well assay plates are available in standard, high bind and tissue culture-treated formats.

You can get in touch with Porvair Sciences Ltd today if you require more information about Microplates new products, or if you have any questions or queries. They recommend going online to browse their full range of 96-well microplates at https://www.microplates.com/solid-bottom/.

Alternatively, you can call 02920 480720, or you can email patricia.deeside@gmail.com for more information.

Source: https://thenewsfront.com/microplates-provides-a-full-range-of-96-well-microplates-including-the-48-and-the-384/

Microplates

Clywedog Road South
Wrexham
LL13 9XS
United Kingdom
+44 (0)1978 661144
Website: https://www.microplates.com/solid-phase-extraction/

Microplates New Products are Available on Their Storage Collection

Microplates new products are available on their storage collection. Porvair Sciences latest addition to the range of Assay plates include the 96 well PP and PS plates. They are proud of these filtration plates as they are specially manufactured under cleanroom conditions, and they are made from polypropylene. This means Porvair can list heat and solvent resistance as another one of their many qualities. Another critical point is that a number of their newest PP and PS 96 well filtration plates are DNase/RNase free.

The Porvair Sciences Assay Plates range offers the most significant combination of good shape, the number of wells and well volume on the market. As a result, most of their PP and PS 96 well plates are made to the ANSI/SLAS standards. Therefore, compatibility is guaranteed with most readers/washers and automated equipment widely used by researchers.

Furthermore, the extension of the PP and PS assay plates brings three new plates with well capacities of 350μl, 270μl and 220μl. This ranges from around bottom to flat (F) bottom and V bottom, the new 96 well plates are perfect for compound storage and culturing.

The microplate company also has a superior range in supply from vacuum manifolds, sealers, evaporators and microfilter plates which Porvair Sciences have stated to be very popular. As well as deep well and shallow good storage plates, assay plates such as the 96 well microplate.

Porvair Sciences also provide custom microplate products for life science research, and they emphasize that the vacuum manifolds are essential for 96-well SPE sample preparation, are designed to work with most popular filter plates, including Waters, Millipore, Qiagen, Whatman, GE Healthcare, Varian, Biotage and not forgetting Porvair itself.

With regards to the 96-well square plates, they were designed to make the interchange of plates simpler in automated systems. There are three plates which have the same geometry, and the only variable is the well depth. For the use of the ‘GenoGrinder™ and TissueLyzer™’ there is a plate available in an extractable-free, medical-grade polymer. The purpose of these plates is for seed and leaf genomic studies. The group of 96-well square plates have a wide range of characteristics such as:

Made from virgin polypropylene
Tested for low extractables
Tight specification levels
V bottom
No inner edges
350µl, 1ml, 1.6ml and 2ml working volumes
Raised well rims
The conical base for sample concentration, reconstitution and centrifugation
Sterile and non-sterile versions

Porvair also has a considerable supply of large volume plates to meet high demands as many requirements have to be met. A lot of time and dedication has gone into the production so you can be assured they will supply you with the highest quality plates in their storage collection, including the 24-well and the 48-well filtration plates. The 48 well features have two versions, one which is 5ml and 44mm high and the other is 68mm high with a 7ml working capacity.

According to Porvair, they have published a detailed analysis of its own and other manufacturer’s plates, with MS traces, this enables the user to compare good and bad performers.

You can get in touch with Porvair Sciences Ltd today if you require more information about Microplates new products, or if you have any questions or queries. They recommend going online to browse their storage collection at https://www.microplates.com/storage-collection. Alternatively, you can call 02920 480720, or you can email patricia.deeside@gmail.com for more information.

Source: https://thenewsfront.com/microplates-new-products-are-available-on-their-storage-collection/

Company Name: Microplates
Contact Person: Patricia Deeside
Email: Send Email
Phone: +44 (0)1978 661144
Address:Clywedog Road South Wrexham Industrial Estate
City: Wrexham LL13 9XS
Country: United Kingdom
Website: https://www.microplates.com

Thursday, November 21, 2019

Porvair Sciences Supply Microplate Assays for high-throughput Screening

Porvair Sciences Supply Microplate assays for high-throughput screening. Porvair Sciences manufacture microplate products such as the 384 well plate, and they play a part in serving Life Sciences, Biotechnology, R&D and Molecular Biology with microplate solutions for all applications. Some of the solutions include sample preparation, high-throughput screening, as mentioned above, and these are all administered through the Porvair Sciences global distributor network.

Porvair Sciences supply the microplate assay plates, and they come in a selection of clear polystyrene bottom, glass-bottom and solid bottom assay plates which are designed for absorbance, fluorescence, luminescence and scintillation applications.

With regards to the standard clear polystyrene bottom plates that Porvair Sciences supply, these have bases ‘0.4mm thick’ and they are – ‘moulded from highly polished tools to reduce flow lines, artefacts and scratches’ which ensures excellent results.

The Glass Bottom plates supplied by Porvair have been shown by leading research institutes to be unsurpassed for flatness, linearity and optical clarity. This means it is incomparable to others out on the market today. It is no wonder Porvair supplies a sparkling pure borosilicate glass which is 175µm thick with a flatness tolerance across the plate of +/- 15µm. With these measurements, you can achieve crisp and clear images every time.

Porvair Sciences explain what exactly assay plates are, they are flat cell culture plates consisting of multiple ‘wells’ which can be used as small test tubes. This microplate is considered a standard tool in both scientific research facilities and laboratories worldwide for clinical diagnostic tests. So, what exactly are assay plates? Well, they are used to inspect enzyme-linked immunosorbent, which is at the core of most human and animal diagnostic testing currently performed. For the term assay itself, it is used to describe the process of testing a substance or an object to determine its components.

Porvair Sciences give their outlook on how to get the most from your plate-based assays. They recommend you select the right test and the best tools — for example, assay plates, for the analysis. By choosing assay microplates optimised for the reagents, they explain that this is key to achieve high-quality data.

Also, they advise you on how to select particular assay plates. They believe the most effective and successful step to do before choosing between the different glass-bottom assay plate options is to look at their reflective property. For instance, maybe you require opaque assay plate walls that prevent well-to-well cross talk. Porvair suggests solid dirty plates if your assay involves – ‘scintillation, fluorescence and luminescence.’

Porvair state that high-throughput applications commonly use 96 well microplates (a measurement of 8 x 12), as a preferred screening format. This assay plate measures cell proliferation, binding interactions, enzyme activity. These assay plates are a favourite for a range of heterogeneous and homogeneous assays.

Furthermore, the assays which can be performed in their assay microplates vary from ‘scintillation and immunoassays to highly sensitive luminescence and fluorescence-based assay’. As well as analysing assays in 96 well assay plates, there are many developments in the process from full screening automation and miniaturising assays in high-density cell culture microplates.

You can contact Porvair Sciences Ltd today if you require more information about Microplates assays for high-throughput screening plate-based assays. You can call 02920 480720. Alternatively, you can email patricia.deeside@gmail.com, or you can go online to their website and read about assay plates at https://www.microplates.com/assay-plates/.

Source: https://thenewsfront.com/porvair-sciences-supply-microplate-assays-for-high-throughput-screening/

Porvair Sciences Offer a Range of Filter Plates for Filtration Applications

According to Porvair Sciences, filtration plates are used in their purest form to remove particulate matter from liquid. That means either the particulate matter or the filtrate is needed for further study.

As mentioned, Porvair Sciences has a range of filter plates, and they have optimised these filter plates for applications including cell harvesting, DNA separations, binding studies, plasmid isolation, general filtration and sample clean-up.

Porvair Sciences expertise and experience lies in polymer moulding, surface treatment, specialist assembly and a general understanding of life science applications which makes the company ideal for custom manufacture.

Porvair Sciences has a range of filter plates including 48-well microplates, filtration plates 96-well, 300µl, 96-well, 400µl, 96-well, 800µl, and 96-well, 2ml.

With the filtration Plates 96-well, 300µl, the product description details are as follows; 96 well polypropylene, 300uL Long drip Hydrophilic PVDF, mean pore size 0.45µm, and for the other products the Long drip options are polypropylene, glass fibre and the same with short drip options.

For the filtration plates 96-well, 400µl, Porvair Sciences has a range of filter plates to suit most filtration applications, including this range of 96-well, 400µl, microplates which contains a variety of polyethene filtration materials. Similarly, with the filtration plates 96-well, 2ml, there is a choice of glass fibre, nylon etc.

Porvair Sciences have made a vast improvement with filter plates for applications including ‘cell harvesting, DNA separations, binding studies, plasmid isolation, general filtration and sample clean-up.’

According to Porvair Sciences, they have a long history of successfully helping customers develop new and innovative microtiter plates and equipment.

Porvair Sciences expertise in polymer moulding, surface treatment, specialist assembly and a general understanding of life science applications makes the company ideal for custom manufacture.

Porvair Sciences can also undertake ‘private labelling’ of their standard products. Their current customers for custom manufacture include the following groups:

Scientific instrument companies
Pharmaceutical R&D laboratories
Cell biology companies
Compound library suppliers
Diagnostic companies
Military contractors
Microarray research companies

Also, there are several techniques which Porvair Sciences use in the generation of custom products which include:

Polymer ultrasonic welding
Plasma surface treatment of polymers
‘Two-shot’ injection moulding
Co-sintering of polymers/silicas

Some of their new plates the Porvair Sciences 96 well PP and PS plates have many key features and benefits. Firstly, they are made to the ANSI/SLAS standards, which is extremely important as this ensures compatibility with most readers/washers and automated equipment widely used by researchers.

Porvair Sciences manufacture assay microplates using highly polished tools to reduce flow lines, artefacts and scratches, guaranteeing excellent results with all types of bottom-reading instruments.

There is also no compromise in quality and rigidity, and the microplates are manufactured from virgin polypropylene and crystal polystyrene. The round or V bottom of the plates allows for more significant liquid removal and particulate collection, while the raised rims improve sealing and stop cross-contamination.

Contact https://www.microplates.com/storage-collection/ today if you require more information about filter plates for filtration applications. If you have any questions or queries, you can call +44 (0)1978 661144 or email patricia.deeside@gmail.com

SOURCE: https://thenewsfront.com/porvair-sciences-offer-a-range-of-filter-plates-for-filtration-applications/

Monday, October 7, 2019

Porvair Sciences Specialise in the Manufacture of Microplate Products for Life Science Research

Microplates specialise in the manufacture of microplate products, and they would also like to mention that they serve Life Sciences, Biotechnology, R&D and Molecular Biology with microplate solutions for all applications.

This includes sample preparation and high throughput screening with its global distributor network.

Porvair Sciences have a range of products which includes everything from – ‘vacuum manifolds, sealers, evaporators and microfilter plates in all popular styles.’ As well as ‘deep well and shallow good storage plates, assay plates, luciferase reporter gene plates and even liquid handling reagent reservoirs.’

The microplates company also provide custom microplate products for life science research, including 96-well SPE sample preparation. They are designed to work with filter plates such as ‘Waters, Millipore, Qiagen, Whatman, GE Healthcare, Varian, Biotage and Porvair.

On their website Microplates, Porvair Sciences has a storage collection that you can browse through. First, you have deep, good polypropylene microplates, which are commonly used for sample storage in life science laboratories. An essential factor to take into consideration with the manufacture of these plates is the selection of clean raw materials for injection moulding.

What is so unique about polypropylene, is that it is an inert and heat resistant material, which is perfect for sample storage. Although all grades of polypropylene are not the same, take for instance injection moulding, grades of polypropylene often have high concentrations of chemicals to aid the moulding process.

This then creates rapid production of plates and lowers costs, at the risk of possibly compromising the integrity of samples or compounds because they are stored in such plates for extended periods.

The problem is acute where compounds are stored as solutions in solvents such as methanol or DMSO, as these excellent solvents tend to extract from the polypropylene base material any added extractable compounds such as mould release agents or polymer flow improvers.

According to the Microplates website, Porvair Sciences has published a detailed analysis of its own and other manufacturer’s plates, with MS traces, so that you can compare good and bad performers.

So, within the storage collection, you have the Deep Well Centrifuge & GeoGrinder accessories, the deep well square, and the deep well round.

Under the Deep Well Centrifuge & GeoGrinder accessories, you have the centrifuge support plate. These are designed to fit into the skirt (the border) of the deep well plates. This then allows the plate to be used in a centrifuge without the risk of the plate distorting, cracking or breaking, causing the well to leak.

For the Deep Well Square, the family of 96-well square plates were designed so that they would make the interchange of plates simpler in automated systems. Interestingly, all of the three plates have the ‘same geometry, and the only variable’ (the part that can be adjusted) is the excellent depth.

Then for the Deep Well Round, the plates are made in virgin polypropylene to minimise extractable. The working volume is 1ml per well, and the total amount is 1.1ml. Coloured plates are highly beneficial as they aid identification when retrieving from storage.

Porvair Sciences Ltd has a long history of successfully helping customers develop new and innovative microlitre plates and equipment.

They also offer quick and efficient solutions to problems from consultancy, design to speedy prototyping for biotech, pharmaceutical and life science companies.

You can get in touch with https://thenewsfront.com/porvair-sciences-specialise-in-the-manufacture-of-microplate-products-for-life-science-research/ today if you require more information or if you have any questions or queries. You can call 02920 480720 or you can email patricia.deeside@gmail.com

SOURCE: https://thenewsfront.com/porvair-sciences-specialise-in-the-manufacture-of-microplate-products-for-life-science-research/

Tuesday, August 20, 2019

Porvair Sciences Manufacture a Wide Range of Microplate Products

Porvair Sciences manufacture a wide range of microplate products, as well as specialise, as well as serve Life Sciences, Biotechnology, R&D and Molecular Biology with microplate solutions for all applications, for example, sample preparation through their global distributor network. They also manufacture microplate products such as the 96 well plate.

The deep well microplates are commonly used for sample storage in life science laboratories. There is an important aspect associated with the manufacture of these plates, which is the selection of clean raw materials for injection moulding.

They are made of polypropylene, which is an inert and heat resistant material, ideal for sample storage. However, all grades of polypropylene are not the same; for example, injection moulding grades of polypropylene often have high concentrations of chemicals to aid the moulding process. This allows rapid production of plates and lower costs, but may compromise the integrity of samples or compounds which are stored in such plates for extended periods.

With regards to one of the microplates, the 96 deep well plate was designed so that it would make the interchange of plates simpler in automated systems. So, for applications using the GenoGrinder™ and TissueLyzer™, a specially reinforced version of this plate is available with extractable-free, medical-grade molecules called polymer.

The microplate 96 well is specifically for seed and leaf genomic studies, which is an area within genetics that focuses on the analysis of an organism. The microplate 96 well is also:

Made from virgin polypropylene
Tested for low extractables
Tight specification levels
It can allow total liquid removal
There are no inner edges
Manufactured under DNase/ RNase free environment
Working volumes of 350µl, 1ml, 1.6ml and 2ml
Raised well rims to improve heat sealing
It has a conical base
Sterile and non-sterile versions

These microplates are made in virgin polypropylene to minimise extractable. Their maximum volume is 2.075 ml per well, and working volume is a useful 1.85 ml, more than any other comparable ‘2 ml Round Well’ plate in this class.

There is a design called the ‘common wall’ which allows the highest possible volume to be used while maintaining an overall height of just 45 mm, complete with ANSI/SLAS standard base and footprint.

Fortunately, Porvair Sciences has developed several storage/collection plates to help in the fields of cell biology, molecular biology, drug discovery, combinatorial chemistry, screening and genomics (an area within genetics).

The plates are manufactured in proper room conditions, and a significant number are DNase/RNase free. They are mainly made from polypropylene, which is inert material giving heat and solvent resistant qualities.

At Porvair Sciences, there is a new range of low profile 1.1ml 96-well round plates. Thus, more plates can be stored or stacked in a given space. As mentioned previously, since the plates are made with extractable-free polypropylene, this, in turn, gives excellent results. Also, there is a specific anti-evaporation cap mat available.

Porvair Sciences offers the most significant combination of excellent shape, several wells and well volume on the market. Each one of the good microplates is in the ANSI/SBS format, this is found on most washers and mechanical equipment.

Contact the Microplates team today if you require more information or if you have any questions or queries. You can call 02920 480720 or email us on cbrownhill@spindogs.com

SOURCE:https://thenewsfront.com/porvair-sciences-manufacture-a-wide-range-of-microplate-products/.

Company Name: Microplates
Contact Person: Chelsea Brownhill
Email: Send Email
Phone: +44 (0)1978 661144
Address:Clywedog Road South Wrexham Industrial Estate
City: Wrexham LL13 9XS
Country: United Kingdom
Website: https://www.microplates.com

Porvair Sciences Offers a Complete Range of Products to Implement SPE

Porvair Sciences offers a wide range of products to implement SPE extraction. Solid-phase extraction (SPE) is a method of sample preparation that concentrates and purifies analytes from solution by sorption, followed by elution of the analyte with a solvent appropriate for instrumental analysis, such as LC-MS.

MicroLute™ is the original SPE 96-well plate format for SPE. According to Porvair Sciences, the device consists of a ‘polypropylene 96-well plate loaded with a choice of sorbent and sorbent volumes’. Also, they mention that the frits have a ‘mean pore size of 20 microns and are made from microporous high-density polyethylene’.

Solid-phase extraction uses the difference of attraction between an analyte and interferents, present in a liquid matrix, for a solid phase (sorbent). It is the attraction that allows the separation of the target analyte from the interferents.

There are several steps involved with a solid-phase extraction; they include:

First, the cartridge is conditioned with a solvent to wet the sorbent. After that, the loading solution containing the analyte is infiltrated through the solid phase (SP). Ideally, the analyte and some impurities are retained on the sorbent. The sorbent is then washed to remove impurities, and the analyte is collected during this elution step.

Porvair Sciences have a vast range of products which includes; vacuum manifolds, sealers, evaporators and microfilter plates, deep well and shallow good storage plates, assay plates, luciferase reporter gene plates and liquid handling reagent reservoirs.

Porvair Sciences also provides custom microplate products for life science research. Their vacuum manifolds are essential for 96-well SPE sample preparation, are designed to work with most popular filter plates, including Waters, Millipore, Qiagen, Whatman, GE Healthcare, Varian, Biotage and, of course, Porvair.

Porvair Sciences mention in their words that solid-phase extraction (SPE) is a sample preparation technique generally used in analytical laboratories for the removal of analytes from a complex matrix. This sample preparation technique helps with the extraction, the clean-up and the concentration of analytes before their quantification.

Additionally, solid-phase extraction can take less the chances of problems occurring, with liquid-liquid extraction, and this, in turn, improves quantitative recovery yields. It is a quick technique (most extraction in less than 30 min), easy to perform and can be automated. Also, this technique is suitable for the pre-treatment of complex matrices such as urine, blood, food samples, water etc.

A broad range of phases exists for SPE. Most of them are based on ionic, hydrophobic or polar interactions. Their selectivity is limited, and the target analyte often co-elutes with interfering compounds. On the other hand, there are molecularly imprinted polymers are the most highly selective phases available today. This technology enables to reduce the presence of interferents during the elution step and obtain higher recoveries in chromatography analysis even at low levels.

Porvair Sciences are experts in the business, and of the development of molecularly imprinted polymers, they have developed a range of selective solid Phase Extraction sorbents using the molecular imprinting procedure for sample clean-up before analysis.

It is evident that solid-phase extraction is a well-established technique, and fortunately, Porvair Sciences offers a wide range of products to implement the SPE extraction.

Contact Microplates today if you require more information about SPE extraction, SPE plates or SPE frits. If you have any questions or queries, you can call +44 (0)1978 661144 or email cbrownhill@spindogs.com

SOURCE:https://thenewsfront.com/porvair-sciences-offers-a-complete-range-of-products-to-implement-spe/.